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NOVOSIBIRSK, August 6 The development of nature-like technologies in the future will lead to the discovery of approaches for quickly stopping bleeding, healing wounds and regenerating human tissue, and for agriculture to provide much greater productivity without long selection mechanisms, Russian scientist, professor at Juntendo University (Tokyo, Japan) Oleg Gusev told reporters in Novosibirsk.
In November last year, Russian President Vladimir Putin issued a decree instructing the Russian government to develop and approve an action plan for the development of nature-like technologies in the country within six months.
«Nature-like technologies, biomimetics, when we create technologies based on what we spied in living nature. For example, insects, the larva of which can survive without water. This is a real species that exists in Africa and is already experiencing drought. The spiny mouse (akomis), which can lose 80% of the skin and restore the skin without a single scar… The main extremophile is the chicken. Chicken eggs develop at a normal temperature of 37 degrees and stop development if they are cooled…,” Gusev said on the sidelines of the 14th international conference “Bioinformatics of Regulation”. and genome structures/systems biology», BGRSSB-2024).
He noted that currently scientists, using the newly opened modern capabilities of accessible genome analysis and big data analysis in bioinformatics, are trying to understand the mechanisms of such unusual capabilities in real living organisms and ways to apply this knowledge to humans.
«For example, we understand that a person cannot grow a cut ear, but an acomis can. Why? In terms of the animal world, a mouse is not very far from a human and, accordingly, the genome system is very close. Having understood how the structure of the acomis is arranged and how ordinary fibroblast cells are reprogrammed into chondrocyte cells (the basis of cartilage), this is a direct exit to biotechnological approaches, at least stimulating improved wound healing and regeneration in humans,» the scientist said, noting that acomis mice also have an unusual ability to instantly stop bleeding without thrombus formation, which is a «biomimetic clue» for the development of new drugs.
«There is no need to create a human with the Acomis gene… that's fantastic. Evolution went through a gradual change in basic biochemical processes and an understanding of the balance of their participants… The drugs we take do not change our genome, they help specific biochemical processes. This is a very natural, understandable and understandable path,» Gusev explained.
The scientists added that nature-like technologies are also very important in agriculture. For example, by understanding the biochemical processes occurring at the genome level in laying hens, it is possible to use food additives to stimulate those that allow them to lay eggs longer, which means saving millions of rubles on purchasing material abroad or years of genomic selection.
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