In Russia they have learned to use bifidobacteria for wound healing

MOSCOW, December 19. Scientists from Tyumen Medical University (TMU) studied the effect of secondary metabolism products of bifidobacterium (Bifidobacterium bifidum) on the properties of human skin cells. According to them, they have found that these products enhance the healing processes of cuts and burns, and medicinal sprays and ointments can be developed based on them. The results of the study were published in the journal Medical Immunology.
According to university experts, a key role in wound healing belongs to fibroblasts — skin cells that synthesize collagen, elastin, hyaluronic acid and other important components responsible for the firmness and elasticity of the skin. Scientists today are actively looking for stimulators of these processes. It was found that they are positively influenced by bifidobacteria (Gram-positive anaerobic bacteria, the most important representatives of human microflora).
Employees of the Department of Microbiology and the Research Institute of Medical Biotechnologies and Biomedicine of TMU studied the effect of the supernatant (liquid remaining after sedimentation of insoluble substances) of bifidobacterium (Bifidobacterium bifidum) on the properties of human fibroblasts. They found that the products of secondary metabolism of bifidobacteria enhance the production of elastin and collagen, as well as cytokines of various types, which accelerates wound healing.
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According to the researchers, the products of the secondary metabolism of bifidobacteria have a stressful effect on skin cells that synthesize collagen and stimulate tissue proliferation without unwanted side effects.
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"The supernatant of Bifidobacterium bifidum can be used for accelerated healing without scars of various wounds — from cuts to burns. On its basis, in the future, it is possible to develop various medicinal sprays and ointments,” said Elena Kostolomova, Associate Professor of the Department of Microbiology at TMU.

She noted that the results of the study will help to understand the mechanisms of the immunoregulatory influence of normal human microflora on the processes of repair and regeneration damaged tissues.

In the future, scientists will continue to study the properties of probiotic bacteria.