MOSCOW, November 23. Scientists at Samara University, as part of a research team, have established the level of content of the most important macro- and microcomponents for the body in the drug they are developing from donor blood plasma. According to them, such a domestically produced drug is an urgent need for Russian medicine. The results were presented at the IV All-Russian Conference on Analytical Spectroscopy.
Plasma is the liquid part of the blood, which is needed to move its other elements and makes up more than half of the blood volume in the body. Plasma consists of biological macromolecules – proteins of different types, enzymes and lipids, and also contains nutrients of organic and inorganic nature.
For clinical use, plasma is obtained by fractionation: under the influence of centrifugal forces, blood cells are separated from the liquid and sedimented. Processed plasma is used for the prevention and treatment of infectious diseases, diseases of the circulatory system, to combat various neoplasms and genetic pathologies, experts explained. Such drugs are also irreplaceable in a number of emergency situations.
According to experts, today in the country the healthcare need for blood plasma products is satisfied only by 10%. To solve this problem, researchers from the Samara National Research University named after Academician S.P. Korolev (Samara University) and the Samara Regional Clinical Blood Transfusion Station are developing new domestic drugs from donor plasma.
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"The key task in the development of such drugs is to accurately determine the content and effect of not only target, but also non-target components, such as ions and microelements, which also have a significant effect on the body,” said Igor Platonov, Dean of the Faculty of Physics at Samara University.
During the work, scientists found that the drug being developed contains the necessary ions that are important for health: the balance of sodium, potassium, calcium and chloride ions ensures normal cellular metabolism and regulation of the acidity level of body fluids, as well as water transport between blood vessels and tissues .
Microelements of the new drug, as the creators explained, are involved in the structure-forming processes of cells and tissues, ensure metabolic processes, are part of enzymes and transport proteins, ensure the strength of teeth and bones, the functioning of muscles and the heart , nervous system.
In the future, work with the drug, according to scientists, will be associated with determining the amount of amino acids and peptides it contains.
Samara University is a participant in the Russian state university support program “Priority- 2030″ national project “Science and Universities”.
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